Experimental technologies and computational tools developed by the Tavazoie Lab.
IPOD
Technology for global in vivo monitoring of
protein-DNA interactions in bacteria
PLoS
Biology 19(6):e3001306 2021
Yeast_CRISPRi
An inducible CRISPR interference library for genetic
interrogation of S. cerevisiae biology
Communications
Biology 3(1):723 2020
IVMD
In vivo mRNA Display technology for high-throughput
proteomic analysis using next-generation sequencing
PNAS
117(43):26710 2020
PETRI-seq
A technology for high-throughput bacterial
single-cell RNA sequencing
Nature
Microbiology May 25, 2020
CALM
Technology for generating comprehensive
CRISPR-interference libraries for sensitive genetic interrogation of
bacterial phenotypes
Cell
180(5):1002 2020
IGET
Integrated Genomics Exploration Tools, a suite of tools for
exploring biological pathways and DNA/RNA/protein regulatory elements
associated with large-scale molecular profiles
Molecular
Cell (2007) 28(2):337-50
Molecular
Cell (2009) 36(5):900-911 PLoS
One. 2010 December 29;5(12):e14444 Nature
(2012) 485, 264-268
- TEISER
- A computational framework for de-novo discovery of structural RNA regulatory elements
- Nature (2012) 485, 264-268
- FIRE-pro
- A computational framework for de novo discovery of peptide motifs associated with protein behaviors
- PLoS One. 2010 December 29;5(12):e14444
ADAM
A technology for global mapping of adaptive mutations in
naturally or experimentally evolved bacteria
Nature
Methods. 2009 Aug; 6(8):581-3
- iPAGE
- An information-theoretic algorithm for discovering pathways associated with behaviors of large-scale molecular profiles
- Molecular Cell (2009) 36(5):900-911
- EVE
- A biochemically realistic simulation framework for evolution of molecular networks under selection
- Science (2008) 320 (5881):1313-1317
- FIRE
- An information theoretic algorithm for de novo discovery of DNA and RNA motifs associated with global mRNA expression profiles
- Molecular Cell (2007) 28(2):337-50